need to flesh this one out...
Originally called the DNA Project, Cadmus is a government project which was started to examine and enhance the human genome. It's notable creations include DNAliens, the clone version of Superboy and the clone of WWII hero the Guardian.
Pre-Crisis: Superman's Pal Jimmy Olsen #133 (October 1970)
Post-Crisis: Superman v.2 Annual #2 (1988)